truCOLLECT™, a novel blood collection, stabilization, and DNA extraction system specifically designed for use in NGS

truCOLLECT™, a novel blood collection, stabilization, and DNA extraction system specifically designed for use in NGS
Nucleic acid-based diagnostics are rapidly moving toward next-generation sequencing (NGS). Venipuncture blood is commonly the sample of choice for high quality DNA purification, but the logistics of blood collection, stabilization, shipping/storage, and DNA extraction remain complex. Current blood collection methods require a professional phlebotomist, leak-proof overnight shipping on ice or cold-packs, and a time-critical labor-intensive DNA extraction workflow. Collectively these complexities create logistical and financial barriers for patients, researchers and clinicians. Dried blood holds the potential to overcome these barriers, however, the currently variable collection, variable stabilization, and unreliable DNA extraction, all of which affect yield and
quality, has prevented its adoption for most NGS-based applications.