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AFA-Nanocrystal™ Production Batch-scale (2mL) Cinnarizine (CNZ) Preparation Protocol Part number 010316
The Covaris process, termed Adaptive Focused Acoustics (AFA) uses high frequency non contact ultra sonics derived from medical diagnostic ultrasound imaging and therapeutic lithotripsy applications, such as kidney stone disruption.
Protocol for: Chromatin shearing with SDS detergent buffers Part Number 010298
Application Note: Assessing FFPE DNA Quality: the “Illumina FFPE QC Kit” enables quantitation of improvements in FFPE DNA Extraction Technologies
In this technical note, we used the Illumina FFPE QC kit to assess the quality of DNA extracted from two different extraction technologies using four different types of FFPE samples.
(Application Notes )
This protocol is for the sample preparation of Mycobacteria grown on agar plates or tube-slants for MALDI-TOF MS microorganism identification analysis with the Bruker Biotyper mass spectrometer.
2015 ASM Microbe Poster – Five-Minute Ultrasonic Inactivation and Protein Extraction of Mycobacteria for Identification by MALDI-ToF MS
MALDI-ToF MS (MALDI) has been used for identification of Mycobacteria. However, extraction methods are time consuming, lack standardization, and require pre-inactivation of the organism. Using Adaptive Focused Acoustics (AFA) technology with ultrasonication, we developed a rapid mycobacterial inactivation/protein extraction method called the Ultrasonic Method (USM) and compared it to an existing commercial assay (CM) and […]
Covaris AFA enables an accelerated path to clinical implementation of MALDI-TOF for routine identification of M. tuberculosis and NTB. Many clinical microbiology labs delay validation of MALDI-TOF for ID of Mycobacterium spp, due to the time required and inconvenience of sample preparation. We demonstrate an alternative protocol as compared to heating and tube-extraction. Using Covaris […]
(Data Sheets )
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Covaris provides tools and technologies to improve pre-analytical sample preparation, enable novel drug formulations, and manage compounds in the drug discovery process.