The S220 Focused-ultrasonicator is a versatile, high power system engineered for pre-analytical sample processing with Covaris’ patented Adaptive Focused Acoustics™. Utilizing a spherical acoustic transducer, specifically designed AFA™ Tubes, and advanced electronics, AFA delivers controlled energy precisely and accurately to sample volumes from 25 μl to 10 ml.
The versatility of the S220 Focused-ultrasonicator makes it possible to bring the advantages of AFA to numerous biological and chemical applications including, DNA, RNA, and chromatin shearing, tissue homogenization, cell lysis, compound dissolution, and particle micronization.
The S220 Focused-ultrasonicator is computer controlled by SonoLab™ Software, incorporating preset protocols for standard methods, such as DNA shearing to specific fragment lengths, and easy-to-use-tools for user-defined protocols. The S220 is also compatible with ActiveX control if required for more specialized customer-defined, laboratory automation applications.
Focused-ultrasonicators with AFA Technology operate at high frequencies (500KHz) and, therefore, unlike traditional low frequency laboratory sonicators. AFA is inaudible and does not require sound-proof boxes, hearing protectors, or other unusual precautions for their operation.
The S220 Focused-ultrasonicator is available in higher power (S220X) and robotic capable (S220R) configurations.
If you are interested in applying Covaris technologies to your specific application please contact us.
Bench-top; high intensity acoustic transducer, temperature monitoring device, circulation pump, water bath with safety enclosure
100 Watts Average Power
8” Width x 21” Depth x 13” Height (20 cm x 53 cm x 33 cm)
Approximately 26 lbs (12 kg)
100-240 VAC 500 VA, 50-60 Hz
19°C to 25°C (66°F to 77°C)
30% to 70%
Water Bath Temperature
+5C to +40C; Controllable
Distilled or deionized water only
Notebook compatible; available with system from Covaris
Microsoft Windows XP SP3 minimum or Windows 7
CE, ETL Mark (for Product Safety), WEEE
Complies with Low Voltage Directive 2006/95/EC. Certified to IEC/EN/UL 61010-1:2004 “Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use, Part1: General Requirements”
Complies with radio frequency emissions and immunity requirements for Class A Industrial/Scientific/Medical (ISM) equipment under EN 61326-1:2005, as well as EN 61000-3-2:2004 and EN61000-3-3:1995. These standards meet the essential requirements of the EU EMC Directive 2004/108/EC. Additionally, the instrument meets FCC Part 15 Class A radio emissions requirements for the USA and ICES-003 Class A for Industry Canada.
Covaris provides tools and technologies to improve pre-analytical sample preparation, enable novel drug formulations, and manage compounds in the drug discovery process.