Protocols for Ion Torrent Platforms
Covaris M220 has been tested and validated by Ion Torrent for use with their sequencing platforms. Covaris has developed DNA shearing protocols compatible with the Ion Xpress Plus gDNA Fragment Library Preparation Kit.
Note: The parameters differ from the settings published in our Quick Guide: DNA shearing with M220 Focused-ultrasonicator. Our Quick Guide has been developed using the Agilent 12k DNA Kit and the fragment size distribution representations are not identical between this kit and the Agilent High Sensitivity DNA Kit. We recommend, Ion Torrent users follow the settings developed specifically for Ion Torrent platforms.