High performance sample preparation that grows with your needs
Process 1 to 8 samples in a batch
Upgrade to 96 samples when needed
The versatility of the E220evolution Focused-ultrasonicator makes it possible to bring the advantages of AFA to numerous biological and chemical applications including: DNA and chromatin shearing, tissue homogenization, cell lysis, compound dissolution, and particle micronization. The E220evolution enables multi-sample, batch preparation, capable of processing a wide range of sample types and volumes and may be programed to process from 1 to 8 samples in a single batch. And, when workload increases, the E220evolution can be upgraded to an E220 capable of processing 1-96 samples/run or to an LE220 for high throughput processing without purchasing a new instrument.
Same applications and protocols for all 3 high-throughput instruments
DNA and RNA extraction from FFPE samples with truXTRAC™
DNA and RNA shearing for Next-Generation Sequencing with microTUBEs™
Chromatin shearing for ChIP samples with truChIP™
DNA extraction and purification from dried blood spots (DBS)
Ideal for NeoPrep with up to 8 samples sheared per batch
DNA/RNA Extraction from FFPE Tissue Samples
truXTRAC FFPE DNA Kit (pdf)
truXTRAC™ FFPE DNA microTUBE Kit for chemagen Technology (24) (pdf)
truXTRAC FFPE RNA Kit (pdf)
Protocol for simultaneous extraction and purification of DNA and RNA from FFPE Tissue Samples with truXTRAC (pdf)
If you are interested in applying Covaris technologies to your specific application please contact us.
Bench-top: high intensity acoustic transducer, sample positioning system, temperature monitoring device, circulation pump, and water bath with safety enclosure.
100 Watts Average Power
24” W x 30” D x 19” H (61cm x 76cm x 48cm)
Approximately 110 lbs (50 Kg)
Meets Low Voltage Directive 2006/95/EC. Tested to EN/UL/CSA 61010-1:2004 “Safety Requirements for Electrical Equipment for Measurement, Control and Laboratory Use, Part 1: General Requirements”
System Accessory to the E220evolution system water bath, automatically circulates water through a 0.5micron particulate filter and ultraviolet (UV) lamp system, helps to keep water clean and free of algae growth for up to one year. Uses 100-240VAC. Includes hose connections to E-series water bath.
Notebook (Computer may be supplied by Covaris or by the user).
Windows 7 or newer
Chiller/heater re-circulating system – not included (may be supplied by Covaris or the user).Connect with the 3/8 inch I.D. hoses and quick connect fittings supplied
Meets EMC Directive 2004/108/EC. Tested to EMI emissions requirements for Industrial Scientific or Medical(ISM) equipment EN55011:1998 + A2:2002 Class A Group1 and EMC requirements – Electrical Equipment for Measurement, Control, and Laboratory Use EN 61326-1:2005 Table 2, EN 61000-3-2:2004 and EN 61000-3-3:1995 +A1:2001.
Distilled or deionized water only
Water Temperature Alarm Limit
Can be set at +5.0C to +40.0C
E100-120, 200-240 V~ 50-60Hz, 500 VAC
Ambient Temperature Range
4° to 37° C
Covaris provides tools and technologies to improve pre-analytical sample preparation, enable novel drug formulations, and manage compounds in the drug discovery process.