Small (100 µL) batch to continuous flow
Particle size control from nano to micron size
Combined with an AFA Flow Vessel, true continuous flow manufacturing of nanoformulations is possible. This allows a single technology to be used from early stage Discovery processing with samples as small as 100 µL, to Continuous Flow Manufacturing with PAT feedback control to maintain quality.
Control nucleation and crystal growth using AFA, from small batch to continuous flow API production. Produce nanoparticle sizes below what can be accomplished with traditional methods. Produce tight micron-size distributions, accelerate difficult reactions, and increase yield.
AFA-Liposome formation is achieved at low temperatures, thus maintaining API and lipid integrity that can be degraded using other methods. Mono disperse liposome particles as small as 25 nm are possible without the use of solvents, simplifying production and increasing the range of materials available for use.